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Tae-Wan Kim, Ph.D.

Originally from Seoul, Dr. Kim earned his Ph.D. at Rutgers University in the 1990s. He began studying Alzheimer’s after a family member was diagnosed with the disease, and continued his postdoctoral work at Harvard Medical School. This was where he discovered a mutation in a critical Alzheimer’s disease-associated gene that causes excessive amyloid and calcium production.

After moving to Columbia in 2000, he continued to focus on understanding the genetic and epigenetic mechanisms of Alzheimer’s disease, with emphasis on the identification and validation of new therapeutic targets. His lab currently is involved in three major studies.

Related Research:

Novel Chemical Modulators for BACE1-Mediated Cleavage of Amyloid Beta Precursor Protein Tae-Wan Kim 2018-08-09 Oligomer Collaborative Projects Charles Glabe David Holtzman Paul Greengard Rudy Tanzi Sam Gandy Sangram S. Sisodia Stephen Strittmatter Tae-Wan Kim Virginia Lee 2011-03-01

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Project Description Researchers Funding
Novel Chemical Modulators for BACE1-Mediated Cleavage of Amyloid Beta Precursor Protein 2017, 2018

$300,000
Oligomer Collaborative Projects 2006

$1,550,000

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

McIntire, L. B., Berman, D. E., Myaeng, J., Staniszewski, A., Arancio, O., Di Paolo, G., & Kim, T. W. Reduction of synaptojanin1 ameliorates synaptic and behaviorla impariments in a mouse model of Alzheimer’s disease, Journal of Neuroscience, October 31, 2012, Read More

Di Paolo, G., & Kim, T. W. Linking Lipids to Alzheimer’s Disease: cholesterol and beyond, Nature Reviews Neuroscience, May 30, 2011, Read More

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