Amyloid beta (AĪ²) is the main component of senile plaques, a distinct pathological hallmark in the brain of Alzheimerās disease (AD) patients. AĪ² is generated from amyloid precursor protein (APP) when cleaved by beta- and gamma-secretase enzymes. Instead, when APP is cleaved by alpha-secretase ADAM10 at the middle of the ...
February 1, 2024
The study, led by Cure Alzheimerās Research Consortium member Sam Gandy, M.D., Ph.D., of the Icahn School of Medicine at Mount Sinai, examined how elements in air pollution such as nickel nanoparticles affect the levels of certain peptides in the brain that are found to be at heightened levels in ...
April 15, 2013
64% Increase in Cases Expected by 2025 World-Renowned Harvard Alzheimerās Doctor Discusses Latest Research for Finding a Cure for Alzheimerās in North Sewallās Point North Sewallās Point, FL — Up to 16 million Americans could have Alzheimerās disease by the year 2050 if a prevention or cure is not found during the ...
March 28, 2006
At age 28, Maria Pugliese may not be able to move mountains, but she certainly made an impact when she ran 60 miles across the Andes Mountains and raised more than $3,000 for Cure Alzheimerās Fund.On Feb. 3, Pugliese woke up at the site of the starting line in Chile, ...
January 18, 2012
By Tim Armour From the new findings about oligomers, many supported by Cure Alzheimerās Fund, we know a lot more about the toxicity of the Abeta42 oligomers and how that affects the neural synapses. None of these first or second generation drugs were aimed at stopping Abeta 42 aggregation or oligomerization; ...
April 1, 2010
Julie is joining Cure Alzheimerās Fund as Development and Communications Associate to help provide content and direction to our communications program, support our fundraising efforts, help manage and expand our outreach programs and generally provide administrative support for Cure Alzheimerās Fund and related researchers. Julie has expertise in media content development, ...
April 5, 2011
Cure Alzheimerās Fund (CureAlz) received a $100,000 donation from the sale of generative art created by five celebrated digital artists, organized by Art Blocks in collaboration with The Giving Block. In October, generative art platform Art Blocks hosted reGEN ā an exclusive sale of works by five leading artists from around ...
November 13, 2023
April 16, 2024
New evidenceāfunded by Cure Alzheimerās Fund (CAF) and othersāhas emerged suggesting a strong connection between air pollution and Alzheimerās disease. āThese findings underscore the complexity of this disease,ā says CAF President and CEO Tim Armour, āand emphasize the need for a comprehensive approach to stop it.āĀ While Alzheimerās researchers have theorized ...
June 27, 2016
My late grandmother, Genevieve Madden, was a loving, intelligent, and quick-witted woman. Later in her life, she suffered from Alzheimerās disease and when she eventually succumbed to the disease she was just a shell of her former self. The disease is cruel for those who suffer from it as well ...
August 12, 2015
