Genevieve G. (Goepfert) Lacey, 90, died Monday June 8, 2020 following a lengthy illness. Born in Malden, she was the daughter of the late Joseph & Berthe (Henzi) Goepfert, and the beloved wife of the late Neil F. Lacey, Jr. Genevieve was raised and educated in Needham, and proudly earned ...
June 9, 2020
Surrounded by her children, Patricia Ann McMahon Lord joined her beloved husband, John Lord, Jr., in eternal rest on October 6, 2020. Mom was born in 1932 to Philomena and Edward McMahon and was raised in the Bronx. She married Dad in 1952. They moved to Brewster, NY, in 1961, where ...
October 27, 2020
January 30, 2024
It has long been a controversial theory about Alzheimer’s disease, often dismissed by experts as a sketchy cul-de-sac off the beaten path from mainstream research. But a new study by a team that includes prominent Alzheimer’s scientists who were previously skeptics of this theory may well change that. The research offers ...
June 22, 2018
We propose to comprehensively examine the molecular machinery of biogenesis of extracellular vesicles such as exosomes and microvesicles among different brain cell types (neurons, microglia) in mouse models. Extracellular vesicles are membranous vesicles enclosed by a lipid bilayer and containing the cytosol of their cell of origin. There is a ...
December 24, 2019
The goal of this project is to identify cells that are both most vulnerable and most resistant to Alzheimer’s disease in order to develop drugs that will protect the most vulnerable. At the early stages of Alzheimer’s disease (AD), neurofibrillary tangles (NFT) and neurodegeneration occur only in very specific regions, while ...
November 11, 2011
October 9 — Eli Lilly announced encouraging results yesterday involving their experimental drug Solanezumab. Solanezumab is an antibody aimed at lowering beta-amyloid levels in the brain. In trials lasting 18 months, patients with mild Alzheimer’s symptoms taking Solanezumab showed significantly less cognitive decline — 34% less — compared with patients ...
October 9, 2012
The blood-brain barrier (BBB) is a highly selective membrane barrier, formed by brain endothelial cells, that separates the brain from circulating blood, preventing harmful materials in the blood from entering the brain. BBB disruption occurs in various neurological disorders, including Alzheimer’s disease (AD), which is the most common form of dementia ...
August 9, 2018
Dear Family and Friends, My grandmother, Diane Aeschliman, is in the late stages of Alzheimer’s and I will be running my third half marathon this August in an effort to raise money for the Cure Alzheimer’s Fund. 100% of donations go directly to research. My paternal grandmother and great grandmother also ...
June 26, 2019
Cure Alzheimer’s Fund Chairman and Co-Founder Jeff Morby and Co-Founder Jacqui Morby were featured for their support of Alzheimer’s research in Sunday’s Pittsburgh Post-Gazette. The article highlights Cure Alzheimer’s Fund’s success and the commitment of its founders and board to cover all operating costs. The Post-Gazette also describes the origins of the ...
January 14, 2015
