Novel Soluable Gamma-Secretase Modulators


Building on in vitro characterization of a novel series of soluable gamma-secretase modulators (SGSMs) funded by Cure Alzheimer’s Fund, the current project is a thorough pharmacological or in vivo examination of these molecules to identify the best or “lead” drug candidate.

Funding to Date



Drug Development, Preclinical Drug Development


Steven L. Wagner, Ph.D.

Rudy Tanzi, Ph.D.