Nanobodies to Cross the Blood-Brain Barrier

2016, 2017

The blood-brain barrier (BBB) is a vital barrier between the bloodstream and the brain. This barrier tightly controls which molecules can enter the brain. As a consequence of this barrier, the majority of currently available drugs can’t enter the brain. Importantly, to treat Alzheimer’s disease, drugs need to reach the brain. The aim of this project is to generate a universal tool that can transport drug molecules to the brain.


Funding to Date

$300,000

Focus

Drug Delivery and Design, Drug Discovery

Researchers

Bart De Strooper, M.D., Ph.D.


Maarten Dewilde, Ph.D.