Cure Alzheimer's Fund Cure Alzheimer's Fund

Bruce Lamb, Ph.D.

Executive Director, Paul and Carole Stark Neurosciences Research Institute, Indiana University School of Medicine

After receiving a bachelor’s degree from Swarthmore College in Swarthmore, Pennsylvania, Dr. Lamb earned a Ph.D. from the University of Pennsylvania in Philadelphia and completed a post-doctoral fellowship at Johns Hopkins University in Baltimore. In 1996, he joined the faculty at Case Western Reserve University in Cleveland. There he advanced from Assistant to Associate Professor before accepting a position at the Cleveland Clinic in 2005. Dr. Lamb’s laboratory focuses on the basic science of Alzheimer’s disease, concentrating on both the role of genetics and the role of various types of brain cells, with a particular focus on immune cells in the development and progression of Alzheimer’s, as well as on understanding the biological mechanism that underlies traumatic brain injury as a significant environmental risk factor for the disease.  An established Alzheimer’s researcher and staunch advocate for increased funding for Alzheimer’s and dementia research, Dr. Lamb’s honors and awards include the Alzheimer’s Association National Civic Award, the Zaven Khachaturian Lifetime Achievement Award, and the Jennifer B. Langston Award from the Alzheimer’s Association Cleveland Chapter. Additionally, he is a Fellow in the American Association for the Advancement of Science and a member of the Alzheimer’s Association Medical and Scientific Advisory Council.

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

10. Kloske, C. M., Belloy, M. E., Blue, E. E., Bowman, G. R., … Gate, D., … , Iadecola, C., Johnson, L. A., Kanekiyo, T., … Lamb, B.T., … Marcora, E., … Morganti, J. M., … Ramachandran, K. V., … Tsai, L. H., … Ulrich, J. D., van der Kant, R., … Wellington, C. L., … Zhao, N., Bu, G., Goate, A. M., Holtzman, D. M. Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference, Alzheimer's & Dementia, July 19, 2024, Read More

Claes, C., England, W. E., Danhash, E. P., Kiani Shabestari, S., Jairaman, A., Chadarevian, J. P., Hasselmann, J., Tsai, A. P., Coburn, M. A., Sanchez, J., Lim, T. E., Hidalgo, J. L. S., Tu, C., Cahalan, M. D., Lamb, B. T., Landreth, G. E., Spitale, R. C., Blurton-Jones, M., & Davtyan, H. The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer’s disease mouse model, Alzheimer's & Dementia, February 9, 2022, Read More

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