These projects were made possible from Cure Alzheimer's Fund support.
| Project Description | Researchers | Funding |
|---|---|---|
| Mechanisms of Retinoid X Receptor-Mediated Abeta Clearance in Alzheimers’ Disease |
2011 $100,000 |
|
| Effect of Bexarotene on Abeta in APP Tg Mice Expressing ApoE3 and ApoE4 |
2011 $100,000 |
These published papers resulted from Cure Alzheimer’s Fund support.
Claes, C., England, W. E., Danhash, E. P., Kiani Shabestari, S., Jairaman, A., Chadarevian, J. P., Hasselmann, J., Tsai, A. P., Coburn, M. A., Sanchez, J., Lim, T. E., Hidalgo, J. L. S., Tu, C., Cahalan, M. D., Lamb, B. T., Landreth, G. E., Spitale, R. C., Blurton-Jones, M., & Davtyan, H. The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer’s disease mouse model, Alzheimer's & Dementia, February 9, 2022, Read More
Cramer, P. E., Cirrito, J. R., Wesson, D. W., Lee, C. Y., Karlo, J. C., Zinn, A. E., Casali, B. T., Restivo, J. L., Goebel, W. D., James, M. J., Brunden, K. R., Wilson, D. A., & Landreth, G. E. ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models, Science, March 23, 2012, Read More
