Cure Alzheimer's Fund Cure Alzheimer's Fund

Cristian Lasagna-Reeves, Ph.D.

Associate Professor, Baylor College of Medicine

Cristian Lasagna-Reeves, Ph.D., is an Associate Professor in the Department of Neurology at Baylor College of Medicine. The main focus of his lab is to comprehensively elucidate the cellular and molecular mechanisms involved in the transition that the microtubule-associated protein tau undergoes from its physiological function to aggregated toxic function in neurodegenerative tauopathies. To investigate the mechanisms of these diseases, he has used a broad range of strategies, such as in vitro aggregation assays, disease cellular models, mouse genetic interaction, behavioral studies, and human neuropathology.

Follow Dr. Lasagna-Reeves on X: @LasagnaLab

To learn more about the research Dr. Lasagna-Reeves is doing, visit the Lasagna-Reeves Lab page.

Related Research:

Modulating the Levels of Tau-Seed Interactors to Treat Alzheimer’s Disease Cristian Lasagna-Reeves 2024-05-29

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Project Description Researchers Funding
Modulating the Levels of Tau-Seed Interactors to Treat Alzheimer’s Disease 2024

$200,631

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Martinez, P., Jury-Garfe, N., Patel, H., You, Y., Perkins, A., You, Y., Lee-Gosselin, A., Vidal, R., & Lasagna-Reeves, C. A. Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation, Journal of Alzheimer's Disease, September 1, 2025, Read More

Jury-Garfe, N., Chimal-Juárez, E., Patel, H., Martinez-Pinto, J., Vanderbosch, K., Mardones, M. D., Perkins, A., Prisco, G. V. D., Marambio, Y., Vidal, R., Atwood, B. K., & Lasagna-Reeves, C. A. Tau depletion diminishes vascular amyloid-related deficits in a mouse model of cerebral amyloid angiopathy, Alzheimer's & Dementia, May 9, 2025, Read More

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