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Frank J. Wolters, M.D., Ph.D.

Clinical Epidemiologist, Erasmus University Medical Centre, Rotterdam, the Netherlands

Frank J. Wolters, M.D., Ph.D.,  is a clinical epidemiologist at Erasmus University Medical Centre in Rotterdam, the Netherlands. Dr. Wolters holds an MSc and Ph.D. (cum laude) in clinical neuroepidemiology from Erasmus University and has completed fellowships at the University of Oxford and the Harvard T.H. Chan School of Public Health. His research focuses on the aetiology of vascular cognitive impairment and its relation to Alzheimer’s disease, with the aim of developing secondary preventive interventions against cognitive decline and dementia. Dr. Wolters is a Dutch Research Council Veni laureate and has published over 80 peer-reviewed articles. He is the principal investigator of the ‘SHINOBI’ study investigating personalized management of covert brain ischaemia and is active in several national and international research networks, as well as the executive committee of the ISTAART Vascular PIA.

 

Related Research:

Disentangling the Role of Intracranial Arteriosclerosis in Alzheimer’s Disease Daniel Bos Frank J. Wolters Geert Jan Biessels Julia Neitzel Meike Vernooij 2022-02-10

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Project Description Researchers Funding
Disentangling the Role of Intracranial Arteriosclerosis in Alzheimer’s Disease 2021, 2023

$339,258.55

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Claus, J. J., Vom Hofe, I., van Ijlzinga Veenstra, A., Licher, S., Seelaar, H., de Jong, F. J., Neitzel, J., Vernooij, M. W., Ikram, M. A., & Wolters, F. J. Generalizability of trial criteria on amyloid-lowering therapy against Alzheimer’s disease to individuals with mild cognitive impairment or early Alzheimer’s disease in the general population, European Journal of Epidemiology, March 23, 2025, Read More

Claus, J. J., Rosbergen, M. T., Roshchupkin, G. V., Ikram, M. A., Vernooij, M. W., & Wolters, F. J. Validation of a novel neuroimaging signature for dementia and clinical Alzheimer’s disease in the population-based Rotterdam study, Journal of Alzheimer's Disease, February 16, 2025, Read More

Wolters, F. J., & Labrecque, J. A. Potential impact of unblinding on observed treatment effects in Alzheimer’s disease trials, Alzheimer's & Dementia, February 21, 2024, Read More

van den Beukel, T. C., Wolters, F. J., Siebert, U., Spiering, W., Ikram, M. A., Vernooij, M. W., de Jong, P. A., & Bos, D. Intracranial arteriosclerosis and the risk of dementia: A population-based cohort study, Alzheimer's & Dementia, October 9, 2023, Read More

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