Meng Chen, Ph.D.

Dr. Chen is currently a Research Fellow in the Genetics and Aging Research Unit at Massachusetts General Hospital (MGH). She received her Ph.D. summa cum laude in Neuroscience at Universitat Autònoma de Barcelona (Spain) in 2014. She then moved to Boston to work at Brigham and Women’s Hospital before joining MGH in 2017.

Over the years, Dr. Chen’s research has focused on elucidating the molecular and cellular mechanisms underlying learning and memory in physiological conditions and neurodegenerative diseases. One of her principal areas of interest is to understand how toxic proteins induce synaptic and cognitive impairment in the brain of Alzheimer’s disease. Her current project aims to investigate the role of neurexins in the development of amyloid pathology.

Related Research:

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.

Selected Publications

These published papers resulted from Cure Alzheimer’s Fund support.

Jorfi, M., Park, J., Hall, C. K., Lin, C. J., Chen, M., von Maydell, D., Kruskop, J. M., Kang, B., Choi, Y., Prokopenko, D., Irimia, D., Kim, D. Y., & Tanzi, R. E. Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model, Nature Neuroscience, August 24, 2023, Read More