Seiko Ikezu, M.D.

Associate Consultant I, Department of Neuroscience, Mayo Clinic, Florida

Seiko Ikezu, M.D., is Associate Consultant I at the Department of Neuroscience in the Mayo Clinic in Jacksonville, Florida. Dr. Ikezu’s research focuses on the pathophysiology of autism spectrum disorders and Alzheimer’s disease, with special interest in the role of microglia in neural development and disease spread. Her main goal is development of microglia-specific delivery of antisense oligonucleotide or recombinant lentivirus to target disease spread and synaptic pruning by microglia. She published her work on the beneficial effect of microglial depletion and repopulation in the behavioral outcome of maternal immune activation mouse model and suppression of tau propagation via extracellular vesicle release in an animal model of Alzheimer’s disease. For a complete list of Dr. Seiko Ikezu’s publications, please click here.

Funded Research

These projects were made possible from Cure Alzheimer's Fund support.