Assistant Professor, Associate Consultant I, Department of Neuroscience, Mayo Clinic, Florida
Assistant Professor Seiko Ikezu, M.D., is an Associate Consultant I at the Department of Neuroscience at the Mayo Clinic in Jacksonville, Florida. She graduated from Gunma University School of Medicine in Japan and took a position as a research assistant professor at Boston University before moving to the Mayo Clinic. Dr. Ikezu’s research focuses on the pathophysiology of Alzheimer’s disease and autism spectrum disorders, with a special interest in the role of microglia in disease spread and neuronal development. Her main goal is to establish microglia-specific delivery of antisense oligonucleotide or recombinant lentivirus to target disease spread and altered neuronal network caused by microglial phenotypic change during aging or fetal phase. She published her work about the beneficial effect of microglial depletion on suppressing tau propagation in animal models of Alzheimer’s disease and microglial repopulation in the behavioral outcome of the maternal immune activation mouse model.
