These projects were made possible from Cure Alzheimer's Fund support.
Project Description | Researchers | Funding |
---|---|---|
Adding Genomics and Methylomics to Personalized Disease Prediction for Alzheimer’s Disease (EPIC4AD) |
2023 $116,684 |
|
Personalized Disease Prediction for Alzheimer’s Disease Using Proteome Profiling: The EPIC4AD Study |
2020, 2022 $1,001,874 |
These published papers resulted from Cure Alzheimer’s Fund support.
Ohlei, O., Paul, K., Nielsen, S. S., Gmelin, D., Dobricic, V., Altmann, V., Schilling, M., Bronstein, J. M., Franke, A., Wittig, M., Parkkinen, L., Hansen, J., Checkoway, H., Ritz, B., Bertram, L., & Lill, C. M. Genome-wide meta-analysis of short-tandem repeats for Parkinson’s disease risk using genotype imputation, Brain Communications, April 23, 2024, Read More
Homann, J., Osburg, T., Ohlei, O., Dobricic, V., Deecke, L., Bos, I., Vandenberghe, R., Gabel, S., Scheltens, P., Teunissen, C. E., Engelborghs, S., Frisoni, G., Blin, O., Richardson, J. C., Bordet, R., Lleó, A., Alcolea, D., Popp, J., Clark, C., Peyratout, G., Martinez-Lage, P., Tainta, M., Dobson, R.J.B., Legido-Quigley, C., Sleegers, K., Van Broeckhoven, C., Wittig, M., Franke, A., Lill, C.M., Blennow, K., Zetterberg, H., Lovestone, S., Streffer, J., Kate, M., Vos, S. J. B., Barkhof, F., Visser, P. J., & Bertram, L. Genome-Wide Association Study of Alzheimer’s Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer’s Disease Multimodal Biomarker Discovery Dataset, Frontiers in Aging Neuroscience, March 21, 2022, Read More
Neumann, A., Ohlei, O., Küçükali, F., Bos, I. J., Timsina, J., Vos, S., Prokopenko, D., Tijms, B. M., Andreasson, U., Blennow, K., Vandenberghe, R., Scheltens, P., Teunissen, C. E., Engelborghs, S., Frisoni, G. B., Blin, O., Richardson, J. C., Bordet, R., Lleó, A., Alcolea, D., … EMIF-AD & ADNI study group Multivariate GWAS of Alzheimer’s disease CSF biomarker profiles implies GRIN2D in synaptic functioning, Genome Medicine, October 4, 2023, Read More
Dobricic, V., Schilling, M., Farkas, I., Gveric, D. O., Ohlei, O., Schulz, J., Middleton, L., Gentleman, S. M., Parkkinen, L., Bertram, L., & Lill, C. M. Common signatures of differential microRNA expression in Parkinson’s and Alzheimer’s disease brains, Brain Communications, October 28, 2022, Read More
Sommerer, Y., Dobricic, V., Schilling, M., Ohlei, O., Bartrés-Faz, D., Cattaneo, G., Demuth, I., Düzel, S., Franzenburg, S., Fuß, J., Lindenberger, U., Pascual-Leone, Á., Sabet, S. S., Solé-Padullés, C., Tormos, J. M., Vetter, V. M., Wesse, T., Franke, A., Lill, C. M., & Bertram, L. Epigenome-Wide Association Study in Peripheral Tissues Highlights DNA Methylation Profiles Associated with Episodic Memory Performance in Humans, Biomedicines, November 3, 2022, Read More
Drewelies, J., Hueluer, G., Duezel, S., Vetter, V. M., Pawelec, G., Steinhagen-Thiessen, E., Wagner, G. G., Lindenberger, U., Lill, C. M., Bertram, L., Gerstorf, D., & Demuth, I. Using blood test parameters to define biological age among older adults: association with morbidity and mortality independent of chronological age validated in two separate birth cohorts, GeroScience, September 24, 2022, Read More
Lill, C. M., & Bertram, L. Genome-wide analysis furthers decoding of Alzheimer disease genetics, Nature Reviews Neurology, May 27, 2022, Read More
Youn, C., Grotzinger, A. D., Lill, C. M., Bertram, L., Schmiedek, F., Lövdén, M., Lindenberger, U., Nivard, M., Harden, K. P., & Tucker-Drob, E. M. Genetic associations with learning over 100 days of practice, npj Science of Learning, May 4, 2022, Read More
Dobricic, V., Schilling, M., Schulz, J., Zhu, L. S., Zhou, C. W., Fuß, J., Franzenburg, S., Zhu, L. Q., Parkkinen, L., Lill, C. M., & Bertram, L. Differential microRNA expression analyses across two brain regions in Alzheimer’s disease, Translational Psychiatry, August 29, 2022, Read More
Lill C. M. Transcriptome-wide Association Study in Frontotemporal Dementia Identifies New Disease Loci by In Silico Analysis, Biological Psychiatry, April 15, 2021, Read More
Schilling, M., & Lill, C. M. MicroRNAs as Molecular Biomarkers for Parkinson’s Disease Progression, Movement Disorders, July 5, 2021, Read More
Sommerer, Y., Dobricic, V., Schilling, M., Ohlei, O., Sabet, S. S., Wesse, T., Fuß, J., Franzenburg, S., Franke, A., Parkkinen, L., Lill, C. M., & Bertram, L. Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer’s disease, Alzheimer's Research & Therapy, May 6, 2023, Read More
Sommerer, Y., Ohlei, O., Dobricic, V., Oakley, D. H., Wesse, T., Sedghpour Sabet, S., Demuth, I., Franke, A., Hyman, B. T., Lill, C. M., & Bertram, L. A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples, Clinical Epigenetics, November 1, 2022, Read More
Deecke, L., Homann, J., Goldeck, D., Ohlei, O., Dobricic, V., Drewelies, J., Demuth, I., Pawelec, G., Bertram, L., & Lill, C. M. No increase of CD8+ TEMRA cells in the blood of healthy adults at high genetic risk of Alzheimer’s disease, Alzheimer's & Dementia, January 25, 2024, Read More