These projects were made possible from Cure Alzheimer's Fund support.
Project Description | Researchers | Funding |
---|---|---|
The Development of DNA-Encoded Libraries to Discover Therapeutically Valuable Low Molecular Weight Compounds for Alzheimer’s Disease |
2018 $172,500 |
These published papers resulted from Cure Alzheimer’s Fund support.
Rodriguez-Rodriguez, P., Arroyo-Garcia, L. E., Tsagkogianni, C., Li, L., Wang, W., Végvári, Á., Salas-Allende, I., Plautz, Z., Cedazo-Minguez, A., Sinha, S. C., Troyanskaya, O., Flajolet, M., Yao, V., & Roussarie, J. P. A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer’s disease vulnerable neurons, Brain, March 11, 2024, Read More
Bustos, V. H., Sunkari, Y. K., Sinha, A., Pulina, M., Bispo, A., Hopkins, M., Lam, A., Kriegsman, S. F., Mui, E., Chang, E., Jedlicki, A., Rosenthal, H., Flajolet, M., & Sinha, S. C. Rational Development of a Small-Molecule Activator of CK1γ2 That Decreases C99 and Beta-Amyloid Levels, ASC Chemical Biology, December 11, 2023, Read More
Bettayeb, K., Hooli, B. V., Parrado, A. R., Randolph, L., Varotsis, D., Aryal, S., Gresack, J., Tanzi, R. E., Greengard, P., & Flajolet, M. Relevance of the COPI complex for Alzheimer’s disease progression in vivo, Proceedings of the National Academy of Sciences of the United States of America, April 25, 2016, Read More
Roussarie, J. P., Yao, V., Rodriguez-Rodriguez, P., Oughtred, R., Rust, J., Plautz, Z., Kasturia, S., Albornoz, C., Wang, W., Schmidt, E. F., Dannenfelser, R., Tadych, A., Brichta, L., Barnea-Cramer, A., Heintz, N., Hof, P. R., Heiman, M., Dolinski, K., Flajolet, M., Troyanskaya, O. G., … Greengard, P. Selective Neuronal Vulnerability in Alzheimer’s Disease: A Network-Based Analysis, Neuron, June 29, 2020, Read More