We fund research with the highest probability of slowing, stopping or reversing Alzheimerās disease. Our approach consists of two principals: 1. The research we fund is based on a 4-part roadmap: (1) find all the genes that contribute to risk for the disease; (2) figure out which ones contribute the most and ...
August 21, 2009
Alzheimer’s disease was discovered over 110 years ago. Little was known about the disease and little more was learned. Our founders, frustrated by the slow pace of research into Alzheimer’s disease, decided to leverage their experience in venture capital and corporate start-ups and build a fund designed specifically to accelerate research, ...
September 24, 2017
May 16, 2022
Alzheimerās disease (AD) is the most common form of dementia among older people. The blood-brain barrier (BBB) is a highly selective, permeable barrier that separates the brain from circulating blood. It is formed by brain endothelial cells and prevents harmful materials from the blood from entering the brain. The BBB ...
May 2, 2023
The specific hypothesis behind the proposed research is that presenilin 1 regulates cell fate determination of adult neural progenitor cells by interfering with instructive intercellular signals prevailing within the neural progenitor cell niche, and that expression of the familial AD-linked presenilin 1adversely affects this process.
February 11, 2011
2021 Alzheimerās disease (AD) is the most important cause of dementia in the United States. It is characterized by the accumulation of two proteins in the brain, amyloid beta (AĪ²) and tau. While AĪ² accumulation is necessary for the AD process, the accumulation of tau is linked with cognitive decline, as ...
July 25, 2017
The world already is very familiar with both Alzheimerās disease (AD), primarily a disease that occurs in the elderly, and Down syndrome (DS), a genetic condition present at birth. What many donāt realize is that these two conditions also overlap. By age 40, nearly all people born with Down syndrome ...
July 25, 2014
On June 9, Cure Alzheimer’s Fund supporters and friends gathered for an exclusive presentation by Dr. Sangram Sisodia,Ā who shared his recent research findings showing the Alzheimerās linkĀ to immune responses caused by bacteria in the digestive systemĀ that influence brain pathology. Through a grant provided by Cure Alzheimerās Fund, Dr. Sisodia has alsoĀ conducted ...
June 16, 2016
October 23, 2020
May 18, 2024
