Diabetes-associated SorCS1 regulates Alzheimer’s amyloid-beta metabolism: evidence for involvement of SorL1 and the Retromer Complex

January 30, 2024

Rudolph Tanzi, Sam Gandy

A Comparison of Popular TDT-generalizations for family-based association analysis

January 30, 2024

Christoph Lange

The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta protein level in vivo

January 30, 2024

Robert Moir, Rudolph Tanzi, Zhongcong Xie

TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway

January 30, 2024

Guojun Bu, Huaxi Xu, John Chen

ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components

January 30, 2024

Guojun Bu, Takahisa Kanekiyo

Head-to-Head Comparison of Tau and Amyloid Positron Emission Tomography Visual Reads for Differential Diagnosis of Neurodegenerative Disorders: An International, Multicenter Study

June 18, 2024

Oskar Hansson, Rik Ossenkoppele

Deciphering and Restoring Computational Setpoints in Alzheimer’s Disease Through Sleep-Enhanced Network Homeostasis

Alzheimer’s disease, a debilitating form of dementia, profoundly impairs the brain’s ability to process complex information, gradually eroding memory, understanding and physical control. Despite knowing that the buildup of abnormal proteins like tau and amyloid beta contribute to the disease, the specific breakdowns in how brain cells communicate—and the resulting ...

January 12, 2024

Keith Hengen

Lymphatics in Neurological Disorders: a neuro-lympho-vascular component of multiple sclerosis and Alzheimer’s disease?

January 30, 2024

Jonathan Kipnis

Structure of the complex of an iminopyridinedione PTP4A3 phosphatase inhibitor with human serum albumin

January 30, 2024

Elizabeth R. Sharlow, John S. Lazo

Comparing Performance of Different Predictive Models in Estimating Disease Progression in Alzheimer Disease

August 16, 2021

Ali Ezzati, Richard Lipton