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Richard L. Huganir

Dr. Richard Huganir is a Professor and Director of the Solomon H. Snyder Department of Neuroscience at the Johns Hopkins University School of Medicine and Co-Director of the Johns Hopkins Medicine Brain Science Institute.Ā  He has joint appointments in the Department Biological Chemistry and the Department of Pharmacology.Ā Dr. Huganir completed ...

August 2, 2017

Richard L. Huganir

SFRP1 as a Therapeutic Target and Diagnostic/Prognostic Factor in Alzheimer’s Disease

2022 Patients with Alzheimerā€™s disease (AD) present with a disease-dependent increase in the brain expression of a small glial-derived secreted protein named SFRP1, which interacts with harmful amyloid products (among the culprit of the pathology) and downregulates an enzyme that prevents their generation. Neutralization of SFRP1 activity in mice counteracts several ...

November 4, 2020

Paola Bovolenta, Pilar Esteve

State of the Mind Events

State of the Mind research presentations are private gatherings of donors and prospective donors who come together to hear from a researcher about Alzheimerā€™s disease and the role Cure Alzheimerā€™s Fund is playing in eradicating itā€”funding research that leads to preventing, slowing or reversing the diseaseā€™s progression. These events highlight ...

November 8, 2017

Rudolph Tanzi

Early in his career, Dr. Tanzi worked with Dr. James Gusella to discover the first human genetic markers and use them to find a disease gene (Huntingtonā€™s disease). He went on to first discover the amyloid precursor protein (APP) gene, the first Alzheimerā€™s disease (AD) gene, and he co-discovered the ...

July 20, 2016

Rudolph Tanzi

Stats & Costs

Learn about the rate of occurrence, and costs, impacting the US

September 24, 2017

Joyce H. Day

Joyce Heyne Day, 86, of Lambertville, MI, beloved wife, mother, grandma,Ā and friend, passed away Friday, August 26, 2022, at her home. TheĀ daughter of Frank Jacob and Leota Harder Heyne, she was born onĀ August 14, 1936, and raised in Toledo, OH. She married Charles (Charlie)Ā Day on August 5, 1961, and together ...

October 25, 2022

Robert F. Greenhill

Founder of Greenhill & Company Robert F. Greenhill is the Founder of Greenhill & Co., an investment banking firm. He was formerly Chairman and Chief Executive of Smith Barney and, prior to that, President of Morgan Stanley Group Inc. He graduated from Harvard Graduate School of Business Administration with high distinction as ...

September 19, 2017

BRAIN IMAGING STUDY SUGGESTS FEMALE-SPECIFIC RISK FACTORS FOR ALZHEIMERā€™S DISEASE

Women are twice as likely to develop late-onset Alzheimerā€™s disease (AD) as men, often attributed to women’s longevity. Recent evidence has emerged suggesting that gender-specific risk factors may drive this difference in addition to a longer lifespan. Attention has now shifted towards identifying the factors that put women at higher ...

October 23, 2020