These projects were made possible from Cure Alzheimer's Fund support.
Project Description | Researchers | Funding |
---|---|---|
Characterization of Tau Pathology Heterogeneity Across the Alzheimer’s Disease Spectrum |
2022, 2023 $402,500 |
These published papers resulted from Cure Alzheimer’s Fund support.
Svenningsson, A. L., Bocancea, D. I., Stomrud, E., van Loenhoud, A., Barkhof, F., Mattsson-Carlgren, N., Palmqvist, S., Hansson, O., & Ossenkoppele, R. Biological mechanisms of resilience to tau pathology in Alzheimer’s disease, Alzheimer's Research & Therapy, October 12, 2024, Read More
Collij, L. E., Mastenbroek, S. E., Mattsson-Carlgren, N., Strandberg, O., Smith, R., Janelidze, S., Palmqvist, S., Ossenkoppele, R., & Hansson, O. Lewy body pathology exacerbates brain hypometabolism and cognitive decline in Alzheimer’s disease, Nature Communications, September 14, 2024, Read More
Palmqvist, S., Tideman, P., Mattsson-Carlgren, N., Schindler, S. E., Smith, R., Ossenkoppele, R., Calling, S., West, T., Monane, M., Verghese, P. B., Braunstein, J. B., Blennow, K., Janelidze, S., Stomrud, E., Salvadó, G., & Hansson, O. Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care, JAMA, July 28, 2024, Read More
Leuzy, A., Raket, L. L., Villemagne, V. L., Klein, G., Tonietto, M., … Petersen, R. C., ... Ossenkoppele, R., ... Hansson, O., ... Doré, V. Harmonizing tau positron emission tomography in Alzheimer’s disease: The CenTauR scale and the joint propagation model, Alzheimer's & Dementia, July 23. 2024, Read More
Soleimani-Meigooni, D. N., Smith, R., Provost, K., Lesman-Segev, O. H., Allen, I. E., Chen, M. K., Cho, H., Edwards, L., Janelidze, S., La Joie, R., Mundada, N., Ossenkoppele, R., Stomrud, E., Strandberg, O., Strom, A., Boxer, A. L., Dage, J. L., Gorno-Tempini, M. L., Kramer, J. H., Miller, B. L., …, Hansson, O., Rabinovici, G. D. Head-to-Head Comparison of Tau and Amyloid Positron Emission Tomography Visual Reads for Differential Diagnosis of Neurodegenerative Disorders: An International, Multicenter Study, Annals of Neurology, June 18, 2024, Read More
Mastenbroek, S. E., Vogel, J. W., Collij, L. E., Serrano, G. E., Tremblay, C., Young, A. L., Arce, R. A., Shill, H. A., Driver-Dunckley, E. D., Mehta, S. H., Belden, C. M., Atri, A., Choudhury, P., Barkhof, F., Adler, C. H., Ossenkoppele, R., Beach, T. G., & Hansson, O. Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology, Nature Communications, June 15, 2024, Read More
Groot, C., Smith, R., Collij, L. E., Mastenbroek, S. E., Stomrud, E., Binette, A. P., Leuzy, A., Palmqvist, S., Mattsson-Carlgren, N., Strandberg, O., Cho, H., Lyoo, C. H., Frisoni, G. B., Peretti, D. E., Garibotto, V., La Joie, R., Soleimani-Meigooni, D. N., Rabinovici, G., Ossenkoppele, R., & Hansson, O. Tau Positron Emission Tomography for Predicting Dementia in Individuals With Mild Cognitive Impairment, JAMA Neurology, June 10, 2024, Read More
Salvadó, G., Horie, K., Barthélemy, N. R., Vogel, J. W., Pichet Binette, A., Chen, C. D., Aschenbrenner, A. J., Gordon, B. A., Benzinger, T. L. S., Holtzman, D. M., Morris, J. C., Palmqvist, S., Stomrud, E., Janelidze, S., Ossenkoppele, R., Schindler, S. E., Bateman, R. J., & Hansson, O. Disease staging of Alzheimer’s disease using a CSF-based biomarker model, Nature Aging, March 21, 2024, Read More
Barthélemy, N. R., Salvadó, G., Schindler, S., He, Y., Janelidze, S., Collij, L. E., Saef, B., Henson, R. L., Chen, C. D., Gordon, B. A., Li, Y., La Joie, R., Benzinger, T. L. S., Morris, J. C., Mattsson-Carlgren, N., Palmqvist, S., Ossenkoppele, R., Rabinovici, G. D., Stomrud, E., Bateman, R. J. & Hansson, O. Highly Accurate Blood Test for Alzheimer’s Disease Comparable or Superior to Clinical CSF Tests, Nature Medicine, February 21, 2024, Read More
Young, A. L., Vogel, J. W., Robinson, J. L., McMillan, C. T., Ossenkoppele, R., Wolk, D. A., Irwin, D. J., Elman, L., Grossman, M., Lee, V. M., Lee, E. B., & Hansson, O. Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies, Brain, May 8, 2023, Read More
Zheng, L., Rubinski, A., Denecke, J., Luan, Y., Smith, R., Strandberg, O., Stomrud, E., Ossenkoppele, R., Svaldi, D. O., Higgins, I. A., Shcherbinin, S., Pontecorvo, M. J., Hansson, O., Franzmeier, N., Ewers, M., & Alzheimer's Disease Neuroimaging Initiative Combined Connectomics, MAPT Gene Expression, and Amyloid Deposition to Explain Regional Tau Deposition in Alzheimer Disease, Annals of Neurology, October 14, 2023, Read More
Bocancea, D. I., Svenningsson, A. L., van Loenhoud, A. C., Groot, C., Barkhof, F., Strandberg, O., Smith, R., Alzheimer’s Disease Neuroimaging Initiative, La Joie, R., Rosen, H. J., Pontecorvo, M. J., Rabinovici, G. D., van der Flier, W. M., Hansson, O., & Ossenkoppele, R. Determinants of cognitive and brain resilience to tau pathology: a longitudinal analysis, Brain, March 27, 2023, Read More
Coomans, E. M., van Westen, D., Pichet Binette, A., Strandberg, O., Spotorno, N., Serrano, G. E., Beach, T. G., Palmqvist, S., Stomrud, E., Ossenkoppele, R., & Hansson, O. Interactions between vascular burden and amyloid-β pathology on trajectories of tau accumulation, Brain, September 18, 2023, Read More
Horie, K., Salvadó, G., Barthélemy, N. R., Janelidze, S., Li, Y., He, Y., Saef, B., Chen, C. D., Jiang, H., Strandberg, O., Pichet Binette, A., Palmqvist, S., Sato, C., Sachdev, P., Koyama, A., Gordon, B. A., Benzinger, T. L. S., Holtzman, D. M., Morris, J. C., Mattsson-Carlgren, N., … Bateman, R. J. CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease, Nature Medicine, July 13, 2023, Read More
Mattsson-Carlgren, N., Collij, L. E., Stomrud, E., Pichet Binette, A., Ossenkoppele, R., Smith, R., Karlsson, L., Lantero-Rodriguez, J., Snellman, A., Strandberg, O., Palmqvist, S., Ashton, N. J., Blennow, K., Janelidze, S., & Hansson, O. Plasma Biomarker Strategy for Selecting Patients With Alzheimer Disease for Antiamyloid Immunotherapies, JAMA Neurology, December 4, 2023, Read More