These projects were made possible from Cure Alzheimer's Fund support.
|Pharmacologically Protecting and Rescuing Synapses from Beta Amyloid by Raising Synaptic PSD-95||
|Characterizing the role of LOAD-associated variants of DLGAP1 in AD||
|Normalizing Abeta synaptic depression with drugs targeting PICK1||
|Understanding the Cell Biology Underlying the Effects of Abeta on Synapse||
|Rescue of Synapses in AD Rodent Models||
These published papers resulted from Cure Alzheimer’s Fund support.
Miyazaki T, Takase K, Nakajima W, Tada H, Ohya D, Sano A, Goto T, Hirase H, Malinow R, Takahashi T Disrupted cortical function underlies behavior dysfunction due to social isolation, J Clin Invest., 122(7), Jul 2, 2012, 2690-701, Read More
Wu-Zhang AX, Schramm CL, Nabavi S, Malinow R, Newton AC Cellular pharmacology of protein kinase Mζ (PKMζ) contrasts with its in vitro profile: implications for PKMζ as a mediator of memory, J Biol Chem., 287(16), Apr 13, 2012, 12879-85, Read More
Kessels HW, Nguyen LN, Nabavi S, Malinow R The prion protein as a receptor for beta-amyloid, Nature, 466(7308), Aug 12, 2010, E3-E5, Read More
Wei W, Nguyen L, Kessels HW, Hagiwara H, Sisodia S, Malinow R Amyloid beta from axons and dendrites reduces local spine number and plasticity, Nature Neuroscience, 13(2), Feb 2010, 190-196, Read More