These projects were made possible from Cure Alzheimer's Fund support.
Project Description | Researchers | Funding |
---|---|---|
Protection Against APOE4 With Longevity-Promoting Interventions |
2021, 2023 $425,717 |
|
Air Pollution and Alzheimer’s Disease Risk Interact With Premature Aging of Neural Stem Cells and Apolipoprotein E Alleles |
2021, 2022, 2023 $778,283 |
|
Interactions Among TREM2, APOE and Sex |
2017, 2019 $328,570 |
|
Air Pollution and APP processing |
2014 $90,908 |
These published papers resulted from Cure Alzheimer’s Fund support.
Godoy-Lugo, J. A., Thorwald, M. A., Cacciottolo, M., D'Agostino, C., Chakhoyan, A., Sioutas, C., Tanzi, R. E., Rynearson, K. D., & Finch, C. E. Air pollution amyloidogenesis is attenuated by the gamma-secretase modulator GSM-15606, Alzheimer's & Dementia, August 12, 2024, Read More
Finch, C. E., & Thorwald, M. A. Inhaled Pollutants of the Gero-Exposome and Later-Life Health, The Journals of Gerontology, June 13, 2024, Read More
Finch C. E. Senolytics and cell senescence: historical and evolutionary perspectives, Evolution, Medicine, & Public Health, May 3, 2024, Read More
Finch, C. E., & Burstein, S. M. Dementia in the Ancient Greco-Roman World Was Minimally Mentioned, Journal of Alzheimer's Disease, February 13, 2024, Read More
Haghani, A., Cacciottolo, M., Doty, K. R., D'Agostino, C., Thorwald, M., Safi, N., Levine, M. E., Sioutas, C., Town, T. C., Forman, H. J., Zhang, H., Morgan, T. E., & Finch, C. E. Mouse Brain Transcriptome Responses to Inhaled Nanoparticulate Matter Differed by Sex and APOE in Nrf2-Nfkb Interactions, eLife, June 24, 2020, Read More
Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., Jacobs, R. E., Doubal, F. N., Ramirez, J., Black, S. E., Nedergaard, M., Benveniste, H., Dichgans, M., Iadecola, C., Love, S., Bath, P. M., … Zlokovic, B. V. Vascular dysfunction — The disregarded partner of Alzheimer’s disease, Alzheimer's & Dementia, January 1, 2019, Read More
Cacciottolo, M., Wang, X., Driscoll, I., Woodward, N., Saffari, A., Reyes, J., Serre, M. L., Vizuete, W., Sioutas, C., Morgan, T. E., Gatz, M., Chui, H. C., Shumaker, S. A., Resnick, S. M., Espeland, M. A., Finch, C. E., & Chen, J. C. Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models, Translational Psychiatry, January 1, 2017, Read More
Stephen, T. L., Cacciottolo, M., Balu, D., Morgan, T. E., LaDu, M. J., Finch, C. E., & Pike, C. J. APOE, Genotype, and Sex affect microglial interactions with plaques in Alzheimer’s disease mice, Acta Neuropathologica Communications, May 21, 2019, Read More
Trumble, B. C., & Finch, C. E. The Exposome in Human Evolution from Dust to Diesel, Quarterly Review of Biology, December 1, 2019, Read More
Finch, C. E., & Shams, S. Apolipoprotein E and Sex Bias in Cerebrovascular aging of men and mice, Trends in Neurosciences, August 18, 2016, Read More
Haghani, A., Dalton, H. M., Safi, N., Shirmohammadi, F., Sioutas, C., Morgan, T. E., Finch, C. E., & Curran, S. P. Air Pollution alters C. elegans development and lifespan: responses to traffic-related nanoparticulate matter, The Journals of Gerontology: Series A, March 4, 2019, Read More
Haghani, A., Arpawong, T. E., Kim, J. K., Lewinger, J. P., Finch, C. E., & Crimmins, E. Female vulnerability to the effects of smoking on health outcomes in older people, PLoS One, June 4, 2020, Read More
Cacciottolo, M., Morgan, T. E., & Finch, C. E. Age, sex, and cerebral microbleeds in EFAD Alzheimer disease mice, Neurobiology of Aging, February 28, 2021, Read More
Woodward, N. C., Levine, M. C., Haghani, A., Shirmohammadi, F., Saffari, A., Sioutas, C., Morgan, T. E., & Finch, C. E. Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo, Journal of Neuroinflammation, April 14, 2017, Read More
Shkirkova, K., Lamorie-Foote, K., Zhang, N., Li, A., Diaz, A., Liu, Q., Thorwald, M. A., Godoy-Lugo, J. A., Ge, B., D'Agostino, C., Zhang, Z., Mack, W. J., Sioutas, C., Finch, C. E., Mack, W. J., & Zhang, H. Neurotoxicity of Diesel Exhaust Particles, Journal of Alzheimer's disease, October 11, 2022, Read More
Haghani, A., Thorwald, M., Morgan, T. E., & Finch, C. E. The APOE gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans, Alzheimer's & Dementia, November 20, 2020, Read More
Zhang, H., D'Agostino, C., Forman, H. J., Cacciottolo, M., Thorwald, M., Mack, W. J., Liu, Q., Shkirkova, K., Lamorie-Foote, K., Sioutas, C., Pirhadi, M., Mack, W. J., Morgan, T. E., & Finch, C. E. Urban Air Pollution Nanoparticles from Los Angeles: Recently Decreased Neurotoxicity, Journal of Alzheimer's Disease, June 29, 2021, Read More
Yassine, H. N., & Finch, C. E. APOE Alleles and Diet in Brain Aging and Alzheimer’s Disease, Frontiers in Aging Neuroscience, June 10, 2020, Read More
Finch C. E. Air pollution, dementia, and lifespan in the socio-economic gradient of aging: perspective on human aging for planning future experimental studies, Frontiers in Aging, November 13, 2023, Read More
Cacciottolo, M., Morgan, T. E., Saffari, A. A., Shirmohammadi, F., Forman, H. J., Sioutas, C., & Finch, C. E. Traffic-related air pollutants (TRAP-PM) promote neuronal amyloidogenesis through oxidative damage to lipid rafts, Free Radical Biology and Medicine, December 26, 2019, Read More
Nesse, R. M., Finch, C. E., & Nunn, C. L. Does selection for short sleep duration explain huma vulnerability to Alzheimer’s disease?, Evolution, Medicine, and Public Health, January 24, 2017, Read More
Thorwald, M. A., Silva, J., Head, E., & Finch, C. E. Amyloid futures in the expanding pathology of brain aging and dementia, Alzheimer's & Dementia, December 19, 2022, Read More